Pentobarbital will lessen the level or effect of atazanavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known. pentobarbital will reduce the extent or effect of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Loss of, or lowered reaction to tofacitinib might occur when coadministered with potent CYP3A4... https://archersjzlz.anchor-blog.com/11281081/5-simple-statements-about-what-type-of-drug-is-nembutal-explained