Listed here, we clearly show that conolidine, a organic analgesic alkaloid used in standard Chinese medication, targets ACKR3, thus furnishing further evidence of a correlation between ACKR3 and soreness modulation and opening alternative therapeutic avenues for the procedure of Continual discomfort. May possibly aid endorse joint versatility and mobility: https://whatischronicpain11087.dailyhitblog.com/36395246/fascination-about-what-is-conolidine