This methylation profile is by now acquired for the MBL stage3 and continues to be reasonably secure over time. Having said that, some CLL have intratumor variability in certain areas, which can alter the expression of several genes and aid tumor evolution.71 Of note, this variability is larger in U-CLL https://situsjudimbl7734456.timeblog.net/68169498/the-best-side-of-mbl77