You will find there's release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors while in the dorsal horn to minimize afferent soreness transmission and create analgesia. As a result, medication like clonidine that concentrate on alpha-2 receptors can impact the transmission of agony. For those https://clayh146kgd5.mysticwiki.com/user