Here we describe the findings of a unique example of the early techniques adopted in neurosurgery around 5000 years ago. consisting in a double well healed skull trephination associated with a post-cranial traumatic event occurring intra vitam to a young male from the Early Chalcolithic cemetery of Pontecagnano (South Italy. ca. 4. https://www.ivoryjinelle.com/amazing-offer-Ohio-University-Ohio-Bobcats-iPhone-13-Pro-Max-Impact-Case-p22134-limited-grab/