Poor/Intensive Metabolizers, CYP2D6 The development with the active metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Somewhere around 7% of the populace has lowered activity of the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme program. These people today are “poor metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, amongst other https://walterz431ohp4.wikipublicity.com/user