Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. Not like opioids, which bind to µ-opioid receptors during the central nervous technique, conolidine modulates alternate molecular targets. A Science Improvements examine discovered that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabilit... https://bookmarkmiracle.com/story22557619/alternative-natural-pain-relief-to-replace-traditional-painkillers-secrets